doi:10.16597/j.cnki.issn.1002-154x.2025.05.001
从青霉素生产残液中回收叔丁醇和醋酸丁酯工艺的模拟研究
高显丽 丁 灿 全明月 李红海*
（青岛科技大学 化工学院，青岛 266042）
摘 要 从某青霉素生产残液中回收叔丁醇和醋酸丁酯，可降低生产成本，同时减少环境污染。作者采用二甲基亚砜为萃取剂的两段萃取精馏分离工艺，以一个常压萃取精馏塔、一个减压萃取精馏塔和一个常压精馏塔实现醋酸丁酯、叔丁醇和水的彻底分离，利用计算模拟软件 Aspen Plus 对叔丁醇和醋酸丁酯的回收过程进行工艺设计与模拟，并进一步对该工艺进行节能优化，最终达到节能与环保的双重效果，并回收得到纯度达 99%的叔丁醇和醋酸丁酯。
关键词 Aspen Plus 萃取精馏 醋酸丁酯 叔丁醇
Aspen Plus Simulation of the Process for Recovering Tert-butanol and Butyl Acetate from Penicillin Production Residue
GAO Xianli DING Can QUAN Mingyue LI Honghai*
(College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, China)
Abstract Recovering tert butanol and butyl acetate from the production residue of a certain penicillin can reduce production costs and minimize environmental pollution. This article adopts a two-stage extraction and distillation separation process using dimethyl sulfoxide as the extractant. One atmospheric extraction and distillation tower, one vacuum extraction and distillation tower, and one atmospheric distillation tower are used to achieve complete separation of butyl acetate, tert butanol, and water. The recovery process of tert butanol and butyl acetate is designed and simulated using the computational simulation software Aspen Plus, and the process is further optimized for energy saving, ultimately achieving a dual effect of energy saving and environmental protection, and recovering tert butanol and butyl acetate with a purity of 99%.
Keywords Aspen Plus extractive distillation butyl acetate tert-butanol